Auctor: William Ramirez
Date Creaturae: 21 September 2021
Date Update: 22 Ianuarii 2025
Anonim
IGHV and TP53 Sequencing:  Clinical Utility in Chronic Lymphocytic Leukemia (CLL)
Video: IGHV and TP53 Sequencing: Clinical Utility in Chronic Lymphocytic Leukemia (CLL)

Contentus

Quid est geneticae TP53 test?

A test TP53 geneticae mutatione ad formam, quae mutationem in nomine TP53 a gene (tumor dapibus LIII). Assignat aliam rationem est basic unitates sunt ex hereditario per patrem tuum et matrem.

TP53 gene est non adjuvat luxuries vetuit nasci similitudines anorum. Suus 'quae est tumor suppressor. A tumor suppressor gene operatur sicut et in ardua dumos currus. Ponit autem "iaculis« in ergastula tam cito non metiuntur. Si vos have a TP53 mutationem in gene est non potest moderari incrementum in uestris cellulis commorantes. Potest ne cancer cellam augmentum ad domum inritatricem parabolam.

A mutationem fieri potest TP53 hereditario a parentibus, vel acquiritur, vel ab aetate a elit sit error, quod fit in corpore per cellulas.

  • Li-mutationem quae est per hereditarium TP53 Fraumeni syndrome.
  • Li-geneticae Fraumeni syndrome est rara conditione, quod potest crescere vestro periculo quaedam genera cancer.
  • Haec includit pectus cancer cancer, cancer os, leukemia et cancer mollis TEXTUS, et vocavit sarcomas.

Acquiritur (also known as Vicia narbonensis) TP53 mutationes quanto magis communia sunt. Hi sunt mutationes in media fere omnibus casibus de cancer, et multa genera cancer.


Alia nomina: TP53 mutationem analysis, TP53 gene plena analysis, TP53 mutationem Vicia narbonensis

Quid est illud ad usus?

In test esse solebat spectare pro TP53 mutationem. Non enim exercitatione test.Est plerumque datum hominibus secundum familia historia, symptoms, diagnosis de cancer vel prior.

Quid ergo opus est geneticae TP53 test?

Si vos opus enim TP53 test:

  • Praecogniti cum cancer te os TEXTUS mollis nec, ante aetatis suae XLV
  • Praecogniti cum te, pre-Menopausalis pectus cancer, a cerebrum tumor, leukemia et cancer pulmonis apud XLVI annos
  • Vel cum parte corporis coram te XLVI annos
  • Vel ex familiae membra vestra quae sunt praecogniti cum Li Fraumeni syndrome-et / aut ante annis XLV cancer habuisse

Haec sunt signa, ut est, haereditatem TP53 gene mutationem Dei.

Si tu praecogniti cum cancer, nec have a familia historia morbus est, ut haec vestris valetudinis curas provisor ut tentem eum utrum per mutationem TP53 tua potest causare cancer. Si vos have vestri provisor iuvare potest ad mutationem consilii certus quod curatio morbo venturam dicunt, verisimile exitus tui.


Quod fit per geneticae TP53 test?

A sanguine et medulla TP53 solet experiri.

Si vos es questus in sanguinem test, valetudinis curas professionalem et accipies sanguinem vein a sample tui brachium, per parvum foramen acus transire. Acus post infertur sanguis parum aut collecta in phiala uitreo. Ut vos sentio parum cum aculeo acus transire vadit, vel egredi. Plerumque minus id elit.

Si vos es questus a os medulla test, te potest procedure includit sequenti gradus:

  • Latus aut ventrem tuum, youll 'tu dormies super latus tuum: os autem quod fretus esse iudicetur. Maxime probat os medulla, ex in os coxae sunt.
  • Purpura cooperiri corpus ut testis tantum circa situm ostendere.
  • Situs cum ANTISEPTICA REMEDIA et potest purgari debet.
  • Vos mos adepto an iniectio solution corpus rigens remittet. Sic ut dolorem.
  • Cum aream sed torpet, salutem cura provisor tollet gustatum. Vos mos postulo ut mentiri etiam in ipso probat.
  • A salutem cura provisor et uti a tool ut torquet specialis os in medullae ossium TEXTUS Domini ad manum exemplum. Ut quidam sentiunt pressura in in sample cum situm est sublatus.
  • Post test, in salutem cura provisor obtegam, aspersione pulveris os site.
  • Consilium habere aliquem coegi vos domum suam: quoniam data est a leniendo potest coram probat, quam ut te faciente sponso dormitaverunt.

Et opus est facere quicquam praeparet pro test?

Et plerumque non indigent aliqua speciali apparatu in sanguine et medullis ossa test.


An ulla metus tentatis?

Parum autem sanguis periculo experiri. Levi dolor habeatis in livorem acu ad locum, sed abire propere salubria.

Medullae ossium post test, ut sentio valde rigida vel per iniectio site. Paucis plerumque abit. Et sanitas tua cura provisor ut suadeo ut dolorem reliever alicui auxilio.

Quid eventus medium?

Si tu praecogniti cum Li-Fraumeni syndrome est, non dico cancer sed altior periculo plurimorum. Sed si ad mutationem, vos can take gradus ad redigendum periculo vestris: ut,

  • Magis crebris cancer screenings. Cancer est treatable, cum in recens vitium.
  • Faciens lifestyle mutationes, ut questus magis exercitium victu et manducans saniorem
  • Chemoprevention sumptio quibusdam medicamentis vitamins substantias reducere periculum moram vel eget arcu.
  • Removere "at-risk" TEXTUS

Hi gradus mos discrepo fretus vestri valetudo historia et familia background.

Si cancer et praecessi indicant quod acquiritur TP53 mutationem (mutationem inventa, sed habent familia historia cancer et Li-Fraumeni syndrome), vestra provisor potest uti notitia ad auxilium venturam dicunt, quid tibi morbus mos develop et virtutis vestrae curatio.

Learn more about laboratorium expertus, referat extra septa templi, et intellectus results.

Aliud est quod opus scire de TP53 test?

Si tu habes suspicaturus vel diagnosed cum Li-Fraumeni syndrome, a geneticae ut auxilium loqui, ut mente pertractans praevaricationem. A consilio a geneticae specialiter eruditique professionales in genetics et geneticae temptationis. Si nondum expertum esse, in mente iuvare potest intelligere extrema temptaturum et beneficia a tentat. Si expertum esse, in mente iuvare potest intelligere et eventus docebit vos suscipio muneris et aliis resources.

Greek New

  1. American Cancer Congregatio [Internet]. Atlanta: American Cancer Congregatio Inc .; c2018. Oppressor genes Oncogenes et tumore, [XXV Iun updated MMXIV, Iun citatis MMXVIII XXIX]; [Screens circa IV]. Available from: https://www.cancer.org/cancer/cancer-causes/genetics/genes-and-cancer/oncogenes-tumor-suppressor-genes.html
  2. American Cancer Congregatio [Internet]. Atlanta: American Cancer Congregatio Inc .; c2020. Quam autem rem tractabant Targeted Nulla a nisl Cancri; [XXVII Dec MMXIX updated: MMXX citatis XIII May]; [Screens circa IV]. Available from: https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/targeted-therapy/what-is.html
  3. Cancer.net [Internet]. Alexandria (VA) de National American Societas Oncology; c2005-2018. Li-Fraumeni Syndrome; Oct MMXVII [citatis MMXVIII Iun XXIX]; [Screens circa III]. Available from: https://www.cancer.net/cancer-types/li-fraumeni-syndrome
  4. Cancer.net [Internet]. Alexandria (VA) de National American Societas Oncology; c2005-2020. Quae Targeted Therapy: Ian MMXIX XX [XIII May citatis MMXX]; [Screens circa IV]. Available from: https://www.cancer.net/navigating-cancer-care/how-cancer-treated/personalized-and-targeted-therapies/understanding-targeted-therapy
  5. Centra pro Morbus Control et cohibitionem [Internet]. Atlanta: US Department of Sanitas et Humanum Services; Cancer MONITIO et Imperium: Protegendisque probat; [II updated MMXVIII Maii, Iun citatis MMXVIII XXIX]; [Screens circa III]. Available from: https://www.cdc.gov/cancer/dcpc/prevention/screening.htm
  6. Li-Fraumeni syndrome: LFSA Association [Internet]. Holliston (MA), Li Fraumeni syndrome Association; c2018. Li ?: Quid est, OMNIBUS Fraumeni syndrome Association; [Citatis MMXVIII Iun XXIX]; [Screens circa II]. Available from: https://www.lfsassociation.org/what-is-lfs
  7. Mayo Clinic [Internet]. Medical et Research Foundation Institutio et fungebatur; c1998-2018. Medullae ossium biopsy neque postulare, Overview; Ian MMXVIII XII [citatis MMXVIII Iun XXIX]; [Screens circa IV]. Available from: https://www.mayoclinic.org/tests-procedures/bone-marrow-biopsy/about/pac-20393117
  8. Mayo Clinic, Mayoensi Medical Laboratories [Internet]. Medical et Research Foundation Institutio et fungebatur; c1995-2018. Test ID: P53CA: hematologic Neoplasmata naturae, TP53 Spermatophyta Dicotyledones, DNA Sequencing Exons 4-9: Volume et Interpretive; [Citatis MMXVIII Iun XXIX]; [Screens circa IV]. Available from: https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/62402
  9. Mayo Clinic, Mayoensi Medical Laboratories [Internet]. Medical et Research Foundation Institutio et fungebatur; c1995-2018. Test ID: TP53Z: TP53 Gene, plena Gene Analysis: Volume et Interpretive; [Citatis MMXVIII Iun XXIX]; [Screens circa IV]. Available from: https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/35523
  10. MD Anderson Cancer Center [Internet]. In Cancer Center University of Texas MD Anderson; c2018. Analysis TP53 Paramecium tetraurelia; [Citatis MMXVIII Iun XXIX]; [Screens circa III]. Available from: https://www.mdanderson.org/research/research-resources/core-facilities/molecular-diagnostics-lab/services/tp53-mutation-analysis.html
  11. Consumer Merck Manual Version [Internet]. Kenell '(Linnaeus) Merck Belize & Co., Inc .; c2018. Et exploratum os medulla, [Citatis MMXVIII Iun XXIX]; [Screens circa II]. Available from: http://www.merckmanuals.com/home/blood-disorders/symptoms-and-diagnosis-of-blood-disorders/bone-marrow-examination
  12. National Cancri Instituti [Internet]. Bethsatham (MD): US Department of Sanitas et Humanum Services; NCI dictionary Termini tropicum Cancri: chemoprevention; [Citatis MMXVIII Iul XI]; [Screens circa III]. Available from: https://www.cancer.gov/publications/dictionaries/cancer-terms/search?contains=false&q=chemoprevention
  13. National Cancri Instituti [Internet]. Bethsatham (MD): US Department of Sanitas et Humanum Services; Testis est Leo Syndromes geneticae hereditaria; [Citatis MMXVIII Iun XXIX]; [Screens circa III]. Available from: https://www.cancer.gov/about-cancer/causes-prevention/genetics/genetic-testing-fact-sheet
  14. National Cancri Instituti [Internet]. Bethsatham (MD): US Department of Sanitas et Humanum Services; NCI dictionary Termini tropicum Cancri: gene; [Citatis MMXVIII Iun XXIX]; [Screens circa III]. Available from: https://www.cancer.gov/publications/dictionaries/cancer-terms/search?contains=false&q=gene
  15. NeoGenomics [Internet]. Fort Myers (FL) NeoGenomics Laboratories; c2018. Analysis TP53 Paramecium tetraurelia; [Citatis MMXVIII Iun XXIX]; [Screens circa III]. Available from: https://neogenomics.com/test-menu/tp53-mutation-analysis
  16. NIH US National Library of Medicine: Reference Genetics Home [Internet]. Bethsatham (MD): US Department of Sanitas et Humanum Services; TP53 gene; Iun XXVI MMXVIII [citatis MMXVIII Iun XXIX]; [Screens circa II]. Available from: https://ghr.nlm.nih.gov/gene/TP53
  17. NIH US National Library of Medicine: Reference Genetics Home [Internet]. Bethsatham (MD): US Department of Sanitas et Humanum Services; Quid est gene mutationem fieri mutationes et quomodo ?; Iun XXVI MMXVIII [citatis MMXVIII Iun XXIX]; [Screens circa II]. Available from: https://ghr.nlm.nih.gov/primer/mutationsanddisorders/genemutation
  18. A Parrales, p53 Mutant enim Oncogenic Targeting Iwakuma T. Cancer Therapy. Ante Oncol [Internet]. Dec MMXV XXI [citatis MMXX XIII May]; V: CCLXXXVIII. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685147
  19. Medical Center University of Rochester [Internet]. Rochester (NY) Medical Center University of Rochester, c2018. Salutem Vicipaedia Pectus Cancri: Triticum Testing; [Citatis MMXVIII Iun XXIX]; [Screens circa II]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=34&contentid=16421-1
  20. Quest Diagnostics [Internet]. Quest Diagnostics; c2000-2017. Center test, TP53 Spermatophyta Dicotyledones, pronostico; [Citatis MMXVIII Iun XXIX]; [Screens circa III]. Available from: https://www.questdiagnostics.com/testcenter/TestDetail.action?ntc=16515
  21. UW Salutem [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics auctoritati; c2017. Salutem Information: et os medulla Aspiration Biopsia: quomodo se habet; [Updated MMXVII May III, Iul citatis MMXVIII XVII]; [Screens circa V]. Available from: https://www.uwhealth.org/health/topic/medicaltest/biopsy-bone-marrow/hw200221.html#hw200245

Et notitia in site si hoc non possunt, pro medicas curas professionalem seu consilium. Et contact salute vestra cura provisor si habetis quaestiones circa salutem.

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